Diagnosis of perinuclear anti-neutrophil cytoplasmic antibody-associated microscopic polyangiitis in silicotics: case report
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چکیده
منابع مشابه
Diagnosis of perinuclear anti-neutrophil cytoplasmic antibody-associated microscopic polyangiitis in silicotics: case report.
BACKGROUND An association between silica exposure and autoimmune diseases including rheumatoid arthritis, systemic sclerosis, systemic lupus erythematosus, and anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis has been made. CASE PRESENTATION A 56-year-old male presented with silicosis and had an occupational history of precious metal processing for 30 years and a 30 pack-...
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life-supporting for as long as 83 days, does support contribution of xenothymus transplantation to graft survival and suggests a role for induction of T-cell xenotolerance. Therefore, while recognizing that crucial advances have been achieved, we feel that translation of necessarily highly intense and prolonged immunosuppressive regimens to human xenograft recipients will be subject to signific...
متن کاملPulmonary interstitial fibrosis as a presenting manifestation in perinuclear antineutrophilic cytoplasmic antibody microscopic polyangiitis.
Microscopic polyangiitis (MPA) is one of the vasculitides that is included in the pulmonary renal syndromes. Pathologically, MPA has been defined as necrotizing vasculitis with few or no immune deposits, primarily affecting small vessels including arterioles, venules, or capillaries. Pulmonary interstitial fibrosis (PIF) as an accompanying manifestation in MPA has not been widely appreciated. I...
متن کاملAntineutrophil cytoplasmic antibody associated microscopic polyangiitis and sinobronchial syndrome.
Antineutrophil cytoplasmic antibodies (ANCA)are well known to be associated with small sized vessel vasculitic diseases such as microscopic polyangiitis (MPA), allergic granulomatous angiitis (AGA), and Wegener's granulomatosis (WG) (1). One subtype is an antibody against myeloperoxidase (MPO), which stains in a perinuclear pattern (P ANCA)by indirect immunofluorescence (IIF) using a neutrophil...
متن کاملMyeloperoxidase anti‐neutrophil cytoplasmic antibody affinity is associated with the formation of neutrophil extracellular traps in the kidney and vasculitis activity in myeloperoxidase anti‐neutrophil cytoplasmic antibody‐associated microscopic polyangiitis
Anti-neutrophil cytoplasmic antibody (ANCA) is associated with small-vessel vasculitis particularly in the kidneys and can induce the formation of neutrophil extracellular traps (NETs) from primed neutrophils. Recently we have reported that the induction of NETs correlates with ANCA affinity for myeloperoxidase (MPO) and disease activity in patients with MPO-ANCA-associated microscopic polyangi...
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ژورنال
عنوان ژورنال: Annals of Occupational and Environmental Medicine
سال: 2016
ISSN: 2052-4374
DOI: 10.1186/s40557-016-0108-1